PATHOPHYSIOLOGY

                               

                                    This 15th century painting depicts the characteristic "buboes," or swollen                                                             

                                                            lymph nodes, of bubonic plague. The buboes are red at first, but then turn                                           

                                                             a dark purple or black, which lead the disease to be called the Black Death.                                                          

                                                                A fourteenth-century plague epidemic killed 25 million people in Europe.

                                                                                       Corbis Corporation (Bellevue)

                               

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